MYC and EIF3H Coamplification Significantly Improve Response and Survival of Non-small Cell Lung Cancer Patients (NSCLC) Treated with Gefitinib

BACKGROUND: We investigated the incidence of eukaryotic translation initiation factor 3 subunit H (EIF3H) and MYC amplification in non-small cell lung cancer (NSCLC) patients, and whether MYC/EIF3H increased gene copy number affected response to Epidermal Growth Factor Receptor tyrosine kinase inhib...

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Bibliografiset tiedot
Päätekijät: Cappuzzo, Federico, Varella-Garcia, Marileila, Rossi, Elisa, Gajapathy, Sujatha, Valente, Marialuisa, Drabkin, Harry, Gemmill, Robert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774779/
https://ncbi.nlm.nih.gov/pubmed/19204574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e31819a5767
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