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Cytokeratin 8 ectoplasmic domain binds urokinase-type plasminogen activator to breast tumor cells and modulates their adhesion, growth and invasiveness

BACKGROUND: Generation of plasmin is a characteristic of tumor cells, promoting the degradation of extracellular matrix, tumor progression and metastasis. The process is accelerated if plasminogen and plasminogen activator are bound to their cell surface receptors. RESULTS: In this study we show tha...

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Detalhes bibliográficos
Main Authors: Obermajer, Nataša, Doljak, Bojan, Kos, Janko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774675/
https://ncbi.nlm.nih.gov/pubmed/19845941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-88
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