miR-128b is a potent glucocorticoid sensitizer in MLL-AF4 acute lymphocytic leukemia cells and exerts cooperative effects with miR-221

MLL-AF4 acute lymphocytic leukemia (ALL) has a poor prognosis. MicroRNAs (miRNA) are small noncoding RNAs that posttranscriptionally regulate expression of target mRNAs. Our analysis of previously published data showed that expression of miR-128b and miR-221 is down-regulated in MLL-rearranged ALL r...

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Autores principales: Kotani, Ai, Ha, Daon, Hsieh, James, Rao, Prakash K., Schotte, Diana, den Boer, Monique L., Armstrong, Scott A., Lodish, Harvey F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2009
Materias:
Lymphoid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774553/
https://ncbi.nlm.nih.gov/pubmed/19749093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-191619
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