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miR-128b is a potent glucocorticoid sensitizer in MLL-AF4 acute lymphocytic leukemia cells and exerts cooperative effects with miR-221
MLL-AF4 acute lymphocytic leukemia (ALL) has a poor prognosis. MicroRNAs (miRNA) are small noncoding RNAs that posttranscriptionally regulate expression of target mRNAs. Our analysis of previously published data showed that expression of miR-128b and miR-221 is down-regulated in MLL-rearranged ALL r...
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Hauptverfasser: | , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
American Society of Hematology
2009
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774553/ https://ncbi.nlm.nih.gov/pubmed/19749093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-191619 |
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