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Listeriolysin O as cytotoxic component of an immunotoxin

Monoclonal antibodies (mAbs) have been developed over the past years as promising anticancer therapeutics. The conjugation of tumor specific mAbs with cytotoxic molecules has been shown to improve their efficacy dramatically. These bifunctional immunotoxins, consisting of covalently linked antibodie...

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Detalhes bibliográficos
Main Authors: Bergelt, Sabine, Frost, Stefan, Lilie, Hauke
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774431/
https://ncbi.nlm.nih.gov/pubmed/19472336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.130
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