The EBV-encoded Latent Membrane Proteins, LMP2A and LMP2B, Limit the Actions of Interferon by Targeting Interferon Receptors for Degradation

Although frequently expressed in EBV-positive malignancies, the role that Latent membrane protein 2A and 2B (LMP2A, LMP2B) play in the oncogenic process remains obscure. Here we demonstrate a novel function for these proteins in epithelial cells, namely, their ability to modulate signalling from typ...

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Hlavní autoři: Shah, Khilan M., Stewart, Suzanne E, Wei, Wenbin, Woodman, Ciaran B J, O’Neil, John D, Dawson, Christopher W., Young, Lawrence S
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774296/
https://ncbi.nlm.nih.gov/pubmed/19718044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.249
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