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Three Distinct Domains Contribute to Nuclear Transport of Murine Foxp3

Foxp3, a 47-kDa transcription factor, is necessary for the function of CD4+CD25+ regulatory T cells (Tregs), with an essential role in the control of self-reactive T cells and in preventing autoimmunity. Activation of Tregs by TCR engagement results in upregulation of Foxp3 expression, followed by i...

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Bibliografski detalji
Glavni autori: Hancock, Wayne W., Özkaynak, Engin
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774276/
https://ncbi.nlm.nih.gov/pubmed/19924293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007890
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