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Pre-treatment with Toll-like receptor 4 antagonist inhibits lipopolysaccharide-induced preterm uterine contractility, cytokines, and prostaglandins in rhesus monkeys

Intra-uterine infection, which occurs in the majority of early preterm births, triggers an immune response culminating in preterm labor. We hypothesized that blockade of lipopolysaccharide (LPS)-induced immune responses by a Toll-like receptor 4 antagonist (TLR4A) would prevent elevations in amnioti...

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Main Authors: Adams Waldorf, Kristina M., Persing, David, Novy, Miles J., Sadowsky, Drew W., Gravett, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774271/
https://ncbi.nlm.nih.gov/pubmed/18187405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719107310992
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