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Cross-regulation of Signaling and Immune Responses by IFN-γ and STAT1

IFN-γ is an important mediator of immunity and inflammation that utilizes the Jak-STAT pathway to activate STAT1. Many functions of IFN-γ have been ascribed to direct STAT1-mediated induction of immune effector genes, but recently it has become clear that key IFN-γ functions are mediated by crossreg...

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Detalhes bibliográficos
Main Authors: Hu, Xiaoyu, Ivashkiv, Lionel B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774226/
https://ncbi.nlm.nih.gov/pubmed/19833085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.09.002
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