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Role of p53 and Rb in Ovarian Cancer

Ovarian cancer remains a major health concern worldwide, primarily in postmenopausal women. Among the most common genetic alterations in human sporadic epithelial ovarian cancer (EOC) are p53 mutations, defective retinoblastoma (RB) pathway (p16(INK4a)/RB) and activation of oncogenes such as c-myc,...

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Detalles Bibliográficos
Autores principales: Corney, David C., Flesken-Nikitin, Andrea, Choi, Jinhyang, Nikitin, Alexander Yu.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774127/
https://ncbi.nlm.nih.gov/pubmed/18546622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-0-387-68969-2_9
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