Local Interleukin-1-Driven Joint Pathology Is Dependent on Toll-Like Receptor 4 Activation

Toll-like receptors (TLRs) may contribute to the pathogenesis of chronic inflammatory destructive diseases through the recognition of endogenous ligands produced on either inflammation or degeneration of the extracellular matrix. The presence of endogenous TLR agonists has been reported in rheumatoi...

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Autors principals: Abdollahi-Roodsaz, Shahla, Joosten, Leo A.B., Koenders, Marije I., van den Brand, Ben T., van de Loo, Fons A.J., van den Berg, Wim B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2009
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774064/
https://ncbi.nlm.nih.gov/pubmed/19834062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090262
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