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Identification of Host Cytosolic Sensors and Bacterial Factors Regulating the Type I Interferon Response to Legionella pneumophila

Legionella pneumophila is a gram-negative bacterial pathogen that replicates in host macrophages and causes a severe pneumonia called Legionnaires' Disease. The innate immune response to L. pneumophila remains poorly understood. Here we focused on identifying host and bacterial factors involved...

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Detalhes bibliográficos
Main Authors: Monroe, Kathryn M., McWhirter, Sarah M., Vance, Russell E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773930/
https://ncbi.nlm.nih.gov/pubmed/19936053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000665
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