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Direct hepatic differentiation of mouse embryonic stem cells induced by valproic acid and cytokines

AIM: To develop a protocol for direct hepatic lineage differentiation from early developmental progenitors to a population of mature hepatocytes. METHODS: Hepatic progenitor cells and then mature hepatocytes from mouse embryonic stem (ES) cells were obtained in a sequential manner, induced by valpro...

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Detalhes bibliográficos
Main Authors: Dong, Xue-Jun, Zhang, Guo-Rong, Zhou, Qing-Jun, Pan, Ruo-Lang, Chen, Ye, Xiang, Li-Xin, Shao, Jian-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: The WJG Press and Baishideng 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773895/
https://ncbi.nlm.nih.gov/pubmed/19891015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.15.5165
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