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Proinsulin C-peptide elicits disaggregation of insulin resulting in enhanced physiological insulin effects
Using surface plasmon resonance (SPR) and electrospray mass spectrometry (ESI-MS), proinsulin C-peptide was found to influence insulin-insulin interactions. In SPR with chip-bound insulin, C-peptide mixed with analyte insulin increased the binding, while alone C-peptide did not. A control peptide wi...
Tallennettuna:
| Päätekijät: | , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Birkhäuser-Verlag
2006
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773842/ https://ncbi.nlm.nih.gov/pubmed/16845606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-006-6204-6 |
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