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Biosynthesis of the proteasome inhibitor syringolin A: the ureido group joining two amino acids originates from bicarbonate

BACKGROUND: Syringolin A, an important virulence factor in the interaction of the phytopathogenic bacterium Pseudomonas syringae pv. syringae B728a with its host plant Phaseolus vulgaris (bean), was recently shown to irreversibly inhibit eukaryotic proteasomes by a novel mechanism. Syringolin A is s...

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Bibliografische gegevens
Hoofdauteurs: Ramel, Christina, Tobler, Micha, Meyer, Martin, Bigler, Laurent, Ebert, Marc-Olivier, Schellenberg, Barbara, Dudler, Robert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773804/
https://ncbi.nlm.nih.gov/pubmed/19863801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-10-26
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