The inhibitory receptor LILRB4 (ILT3) modulates antigen presenting cell phenotype and, along with LILRB2 (ILT4), is upregulated in response to Salmonella infection

BACKGROUND: Leukocyte Ig-like receptors (LILR) are a family of innate immune receptors with immunomodulatory functions. High-level expression of the receptors LILRB2 (ILT4) and LILRB4 (ILT3) is a feature of tolerogenic antigen presenting cells and has been observed in cancer and transplant situation...

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Main Authors: Brown, Damien P, Jones, Des C, Anderson, Katie J, Lapaque, Nicolas, Buerki, Robin A, Trowsdale, John, Allen, Rachel L
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773765/
https://ncbi.nlm.nih.gov/pubmed/19860908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-10-56
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