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Learning about cancer from frogs: analysis of mitotic spindles in Xenopus egg extracts

The mitotic spindle is responsible for correctly segregating chromosomes during cellular division. Disruption of this process leads to genomic instability in the form of aneuploidy, which can contribute to the development of cancer. Therefore, identification and characterization of factors that are...

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Autors principals: Cross, Marie K., Powers, Maureen A.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Limited 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773725/
https://ncbi.nlm.nih.gov/pubmed/19892884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.002022
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