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The interaction of GSTM1 null variants with tobacco smoke exposure and the development of childhood asthma

BACKGROUND: The glutathione S-transferase M1 (GSTM1) null variant is a common copy number variant associated with adverse pulmonary outcomes, including asthma and airflow obstruction, with evidence of important gene-by-environment interactions with exposures to oxidative stress. OBJECTIVE: To explor...

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Detalhes bibliográficos
Main Authors: Rogers, Angela, Brasch-Andersen, Charlotte, Ionita-Laza, Iuliana, Murphy, Amy, Sharma, Sunita, Klanderman, Barbara, Raby, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773694/
https://ncbi.nlm.nih.gov/pubmed/19860819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2222.2009.03372.x
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