Brain nicotinic acetylcholine receptor occupancy: effect of smoking a denicotinized cigarette

Our group recently reported that smoking a regular cigarette (1.2–1.4 mg nicotine) resulted in 88% occupancy of brain α(4)β(2)* nicotinic acetylcholine receptors (nAChRs). However, this study did not determine whether nicotine inhalation or the many other pharmacological and behavioural factors that...

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Autors principals: Brody, Arthur L., Mandelkern, Mark A., Costello, Matthew R., Abrams, Anna L., Scheibal, David, Farahi, Judah, London, Edythe D., Olmstead, Richard E., Rose, Jed E., Mukhin, Alexey G.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773668/
https://ncbi.nlm.nih.gov/pubmed/18706128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S146114570800922X
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