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Echocardiographic Strain Imaging to Assess Early and Late Consequences of Sarcomere Mutations in Hypertrophic Cardiomyopathy

BACKGROUND: Genetic testing identifies sarcomere mutation carriers (G+) before clinical diagnosis of hypertrophic cardiomyopathy (HCM), allowing characterization of initial disease manifestations. Prior studies demonstrated that impaired relaxation develops before left ventricular hypertrophy (LVH)....

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Autors principals: Ho, Carolyn Y., Carlsen, Christian, Thune, Jens Jakob, Havndrup, Ole, Bundgaard, Henning, Farrohi, Faranak, Rivero, Jose, Cirino, Allison L., Andersen, Paal Skytt, Christiansen, Michael, Maron, Barry J., Orav, E. John, Køber, Lars
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773504/
https://ncbi.nlm.nih.gov/pubmed/20031602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.109.862128
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