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Targeting the Replication Initiator of the Second Vibrio Chromosome: Towards Generation of Vibrionaceae-Specific Antimicrobial Agents

The Vibrionaceae is comprised of numerous aquatic species and includes several human pathogens, such as Vibrio cholerae, the cause of cholera. All organisms in this family have two chromosomes, and replication of the smaller one depends on rctB, a gene that is restricted to the Vibrionaceae. Given t...

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Autori principali: Yamaichi, Yoshiharu, Duigou, Stéphane, Shakhnovich, Elizabeth A., Waldor, Matthew K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773409/
https://ncbi.nlm.nih.gov/pubmed/19936046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000663
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