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Activation of canonical Wnt signaling pathway promotes proliferation and self-renewal of rat hepatic oval cell line WB-F344 in vitro

AIM: To investigate the effect of activation of canonical Wnt signaling pathway on the proliferation and differentiation of hepatic oval cells in vitro. METHODS: WB-F344 cells were treated with recombinant Wnt3a (20, 40, 80, 160, 200 ng/mL) in serum-free medium for 24 h. Cell proliferation was measu...

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Detalhes bibliográficos
Main Authors: Zhang, Ying, Li, Xin-Min, Zhang, Fu-Kui, Wang, Bao-En
Formato: Artigo
Idioma:Inglês
Publicado em: The WJG Press and Baishideng 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773309/
https://ncbi.nlm.nih.gov/pubmed/19034970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.6673
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