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A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling

Meckel syndrome (MKS) is a rare autosomal recessive disease causing perinatal lethality associated with a complex syndrome that includes occipital meningoencephalocele, hepatic biliary ductal plate malformation, postaxial polydactyly and polycystic kidneys. The gene mutated in type 1 MKS encodes a p...

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Autors principals: Weatherbee, Scott D., Niswander, Lee A., Anderson, Kathryn V.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773271/
https://ncbi.nlm.nih.gov/pubmed/19776033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp422
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