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Functional analysis of 5-lipoxygenase promoter repeat variants

Variants of a hexanucleotide repeat polymorphism in the promoter of the 5-lipoxygenase (5-LO) gene have been associated with cardiovascular disease traits in humans, which may be due, at least in part, to differential expression of the at-risk alleles. To more fully characterize these variants, we c...

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Autors principals: Vikman, Susanna, Brena, Romulo M., Armstrong, Patrice, Hartiala, Jaana, Stephensen, Charles B., Allayee, Hooman
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773268/
https://ncbi.nlm.nih.gov/pubmed/19717473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp414
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