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X11β rescues memory and long-term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice

Increased production and deposition of amyloid β-protein (Aβ) are believed to be key pathogenic events in Alzheimer's disease. As such, routes for lowering cerebral Aβ levels represent potential therapeutic targets for Alzheimer's disease. X11β is a neuronal adaptor protein that binds to t...

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Detalhes bibliográficos
Main Authors: Mitchell, Jacqueline C., Ariff, Belall B., Yates, Darran M., Lau, Kwok-Fai, Perkinton, Michael S., Rogelj, Boris, Stephenson, John D., Miller, Christopher C.J., McLoughlin, Declan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773264/
https://ncbi.nlm.nih.gov/pubmed/19744962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp408
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