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Phase II Multi-Institutional Trial of the Histone Deacetylase Inhibitor Romidepsin As Monotherapy for Patients With Cutaneous T-Cell Lymphoma
PURPOSE: Romidepsin (depsipeptide or FK228) is a member of a new class of antineoplastic agents active in T-cell lymphoma, the histone deacetylase inhibitors. On the basis of observed responses in a phase I trial, a phase II trial of romidepsin in patients with T-cell lymphoma was initiated. PATIENT...
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Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
American Society of Clinical Oncology
2009
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773225/ https://ncbi.nlm.nih.gov/pubmed/19826128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.21.6150 |
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