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Matching biochemical reaction kinetics to the timescales of life: Structural determinants that influence the autodephosphorylation rate of response regulator proteins
In two-component regulatory systems, covalent phosphorylation typically activates the response regulator signaling protein and hydrolysis of the phosphoryl group reestablishes the inactive state. Despite highly conserved three-dimensional structures and active site features, the rates of catalytic a...
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Principais autores: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773209/ https://ncbi.nlm.nih.gov/pubmed/19646451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.07.064 |
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