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Functional Energetic Landscape in the Allosteric Regulation of Muscle Pyruvate Kinase II. Fluorescence Study

The energetic landscape of the allosteric regulatory mechanism of rabbit muscle pyruvate kinase (RMPK) was characterized by isothermal titration calorimetry (ITC). Four novel insights were uncovered 1. ADP exhibits a dual property. Depending on the temperature, ADP can regulate RMPK activity by swit...

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Detalhes bibliográficos
Main Authors: Herman, Petr, Lee, J. Ching
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772997/
https://ncbi.nlm.nih.gov/pubmed/19719323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900280u
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