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Functional Energetic Landscape in the Allosteric Regulation of Muscle Pyruvate Kinase II. Fluorescence Study
The energetic landscape of the allosteric regulatory mechanism of rabbit muscle pyruvate kinase (RMPK) was characterized by isothermal titration calorimetry (ITC). Four novel insights were uncovered 1. ADP exhibits a dual property. Depending on the temperature, ADP can regulate RMPK activity by swit...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2772997/ https://ncbi.nlm.nih.gov/pubmed/19719323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900280u |
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