Legionella lipoprotein activates toll-like receptor 2 and induces cytokine production and expression of costimulatory molecules in peritoneal macrophages

Legionella bacterium, an intracellular pathogen of mononuclear phagocytes, causes acute fatal pneumonia, especially in patients with impaired cellular immune responses. Until recently, however, the toll-like receptor (TLR) engagement of bacterial proteins derived from Legionella is uncertain. We pre...

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Main Authors: Shim, Ho Ki, Kim, Jeoung Yeon, Kim, Mi Jeong, Sim, Hee Sun, Park, Dae Won, Sohn, Jang Wook, Kim, Min Ja
Formato: Artigo
Idioma:Inglês
Publicado: Korean Society of Medical Biochemistry and Molecular Biology 2009
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772971/
https://ncbi.nlm.nih.gov/pubmed/19561404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2009.41.10.075
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