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OP-1 Augments Glucocorticoid-inhibited Fracture Healing in a Rat Fracture Model
Glucocorticoids inhibit bone remodeling and fracture healing. We sought to determine whether osteogenic protein 1 (OP-1) can overcome this inhibition in a closed fracture model in the rat. Time-released prednisolone or placebo pellets were implanted subcutaneously; closed femoral fractures were crea...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer-Verlag
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2772924/ https://ncbi.nlm.nih.gov/pubmed/19301082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-009-0782-1 |
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