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OP-1 Augments Glucocorticoid-inhibited Fracture Healing in a Rat Fracture Model

Glucocorticoids inhibit bone remodeling and fracture healing. We sought to determine whether osteogenic protein 1 (OP-1) can overcome this inhibition in a closed fracture model in the rat. Time-released prednisolone or placebo pellets were implanted subcutaneously; closed femoral fractures were crea...

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Bibliografische gegevens
Hoofdauteurs: Gilley, Robert S., Wallace, Larry J., Bourgeault, Craig A., Kidder, Louis S., Bechtold, Joan E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer-Verlag 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772924/
https://ncbi.nlm.nih.gov/pubmed/19301082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-009-0782-1
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