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rhBMP-2 Modulation of Gene Expression in Infected Segmental Bone Defects
The osteoinductive capability of BMPs appears diminished in the setting of acute infection. We applied rhBMP-2 to a segmental defect in a rat femur and measured the expression of key bone formation genes in the presence of acute infection. Types I and II collagen, osteocalcin, and BMP Type II recept...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer-Verlag
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2772904/ https://ncbi.nlm.nih.gov/pubmed/19018606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-008-0599-3 |
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