rhBMP-2 Modulation of Gene Expression in Infected Segmental Bone Defects

The osteoinductive capability of BMPs appears diminished in the setting of acute infection. We applied rhBMP-2 to a segmental defect in a rat femur and measured the expression of key bone formation genes in the presence of acute infection. Types I and II collagen, osteocalcin, and BMP Type II recept...

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Detalhes bibliográficos
Main Authors: Brick, Katherine E., Chen, Xinqian, Lohr, Jamie, Schmidt, Andrew H., Kidder, Louis S., Lew, William D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2008
Assuntos:
Symposium: Tribute to Dr. Marshall Urist: Musculoskeletal Growth Factors
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772904/
https://ncbi.nlm.nih.gov/pubmed/19018606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-008-0599-3
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