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Combined treatment with lexatumumab and irradiation leads to strongly increased long term tumour control under normoxic and hypoxic conditions

PURPOSE: The combination of ionizing radiation with the pro-apoptotic TRAIL receptor antibody lexatumumab has been shown to exert considerable synergistic apoptotic effects in vitro and in short term growth delay assays. To clarify the relevance of these effects on local tumour control long-term exp...

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Autori principali: Marini, Patrizia, Junginger, Dorothea, Stickl, Stefan, Budach, Wilfried, Niyazi, Maximilian, Belka, Claus
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772841/
https://ncbi.nlm.nih.gov/pubmed/19860913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-4-49
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