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A Quantitative Affinity-Profiling System That Reveals Distinct CD4/CCR5 Usage Patterns among Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus Strains

The affinity of human immunodeficiency virus (HIV) envelope for CD4 and CCR5 appears to be associated with aspects of R5 virus (virus using the CCR5 coreceptor) pathogenicity. However, entry efficiency results from complex interactions between the viral envelope glycoprotein and both CD4 and CCR5, w...

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Detalhes bibliográficos
Main Authors: Johnston, Samantha. H., Lobritz, Michael A., Nguyen, Sandra, Lassen, Kara, Delair, Shirley, Posta, Filippo, Bryson, Yvonne J., Arts, Eric J., Chou, Tom, Lee, Benhur
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772777/
https://ncbi.nlm.nih.gov/pubmed/19692480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01242-09
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