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A Quantitative Affinity-Profiling System That Reveals Distinct CD4/CCR5 Usage Patterns among Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus Strains

The affinity of human immunodeficiency virus (HIV) envelope for CD4 and CCR5 appears to be associated with aspects of R5 virus (virus using the CCR5 coreceptor) pathogenicity. However, entry efficiency results from complex interactions between the viral envelope glycoprotein and both CD4 and CCR5, w...

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Hlavní autoři: Johnston, Samantha. H., Lobritz, Michael A., Nguyen, Sandra, Lassen, Kara, Delair, Shirley, Posta, Filippo, Bryson, Yvonne J., Arts, Eric J., Chou, Tom, Lee, Benhur
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772777/
https://ncbi.nlm.nih.gov/pubmed/19692480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01242-09
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