Low pH-Triggered Beta-Propeller Switch of the Low-Density Lipoprotein Receptor Assists Rhinovirus Infection

Minor group human rhinoviruses (HRVs) bind three members of the low-density lipoprotein receptor (LDLR) family: LDLR proper, very-LDLR (VLDLR) and LDLR-related protein (LRP). Whereas ICAM-1, the receptor of major group HRVs actively contributes to viral uncoating, LDLRs are rather considered passive...

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Autores principales: Konecsni, Tuende, Berka, Ursula, Pickl-Herk, Angela, Bilek, Gerhard, Khan, Abdul Ghafoor, Gajdzig, Leszek, Fuchs, Renate, Blaas, Dieter
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772763/
https://ncbi.nlm.nih.gov/pubmed/19706701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01312-09
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