Infection with “Escaped” Virus Variants Impairs Control of Simian Immunodeficiency Virus SIVmac239 Replication in Mamu-B*08-Positive Macaques

An understanding of the mechanism(s) by which some individuals spontaneously control human immunodeficiency virus (HIV)/simian immunodeficiency virus replication may aid vaccine design. Approximately 50% of Indian rhesus macaques that express the major histocompatibility complex (MHC) class I allele...

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Detalhes bibliográficos
Main Authors: Valentine, Laura E., Loffredo, John T., Bean, Alex T., León, Enrique J., MacNair, Caitlin E., Beal, Dominic R., Piaskowski, Shari M., Klimentidis, Yann C., Lank, Simon M., Wiseman, Roger W., Weinfurter, Jason T., May, Gemma E., Rakasz, Eva G., Wilson, Nancy A., Friedrich, Thomas C., O'Connor, David H., Allison, David B., Watkins, David I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772717/
https://ncbi.nlm.nih.gov/pubmed/19726517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01298-09
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