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Insertional Mutations in Herpes Simplex Virus Type 1 gL Identify Functional Domains for Association with gH and for Membrane Fusion

Glycoprotein L (gL) is one of four glycoproteins required for the entry of herpes simplex virus (HSV) into cells and for virus-induced cell fusion. This glycoprotein oligomerizes with gH to form a membrane-bound heterodimer but can be secreted when expressed without gH. Twelve unique gL linker-inser...

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Detalhes bibliográficos
Main Authors: Fan, Qing, Lin, Erick, Spear, Patricia G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772692/
https://ncbi.nlm.nih.gov/pubmed/19726507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01369-09
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