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Nondividing but Metabolically Active Gamma-Irradiated Brucella melitensis Is Protective against Virulent B. melitensis Challenge in Mice

Brucella spp. are gram-negative bacteria that cause the most frequent zoonotic disease worldwide, with more than 500,000 human infections yearly; however, no human vaccine is currently available. As with other intracellular organisms, cytotoxic mechanisms against infected cells are thought to have a...

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Detalhes bibliográficos
Main Authors: Magnani, D. M., Harms, J. S., Durward, M. A., Splitter, G. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772552/
https://ncbi.nlm.nih.gov/pubmed/19703982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00231-09
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