CD46 Transgenic Mouse Model of Necrotizing Fasciitis Caused by Streptococcus pyogenes Infection

We developed a human CD46-expressing transgenic (Tg) mouse model of subcutaneous (s.c.) infection into both hind footpads with clinically isolated 11 group A streptococcus (GAS) serotype M1 strains. When the severity levels of foot lesions at 72 h and the mortality rates by 336 h were compared after...

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Hlavní autoři: Matsui, Hidenori, Sekiya, Yukie, Nakamura, Masahiko, Murayama, Somay Yamagata, Yoshida, Haruno, Takahashi, Tetsufumi, Imanishi, Ken'ichi, Tsuchimoto, Kanji, Uchiyama, Takehiko, Sunakawa, Keisuke, Ubukata, Kimiko
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Bacterial Infections
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772545/
https://ncbi.nlm.nih.gov/pubmed/19737905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00577-09
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