SgrA, a Nidogen-Binding LPXTG Surface Adhesin Implicated in Biofilm Formation, and EcbA, a Collagen Binding MSCRAMM, Are Two Novel Adhesins of Hospital-Acquired Enterococcus faecium

Hospital-acquired Enterococcus faecium isolates responsible for nosocomial outbreaks and invasive infections are enriched in the orf2351 and orf2430 genes, encoding the SgrA and EcbA LPXTG-like cell wall-anchored proteins, respectively. These two surface proteins were characterized to gain insight i...

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Bibliographic Details
Main Authors: Hendrickx, Antoni P. A., van Luit-Asbroek, Miranda, Schapendonk, Claudia M. E., van Wamel, Willem J. B., Braat, Johanna C., Wijnands, Lucas M., Bonten, Marc J. M., Willems, Rob J. L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772516/
https://ncbi.nlm.nih.gov/pubmed/19737906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00275-09
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