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Conservation of the Sterol Regulatory Element-Binding Protein Pathway and Its Pathobiological Importance in Cryptococcus neoformans

The mammalian sterol regulatory element-binding protein (SREBP) homolog, Sre1, is important for adaptation and growth of Cryptococcus neoformans in the mouse brain, where oxygen concentration and nutritional conditions are suboptimal for fungal growth. The extent of conservation of the SREBP pathway...

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Bibliografiske detaljer
Main Authors: Chang, Yun C., Ingavale, Susham S., Bien, Clara, Espenshade, Peter, Kwon-Chung, Kyung J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772393/
https://ncbi.nlm.nih.gov/pubmed/19749173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00207-09
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