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Conservation of the Sterol Regulatory Element-Binding Protein Pathway and Its Pathobiological Importance in Cryptococcus neoformans

The mammalian sterol regulatory element-binding protein (SREBP) homolog, Sre1, is important for adaptation and growth of Cryptococcus neoformans in the mouse brain, where oxygen concentration and nutritional conditions are suboptimal for fungal growth. The extent of conservation of the SREBP pathway...

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Bibliographic Details
Main Authors: Chang, Yun C., Ingavale, Susham S., Bien, Clara, Espenshade, Peter, Kwon-Chung, Kyung J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772393/
https://ncbi.nlm.nih.gov/pubmed/19749173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00207-09
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