Cellular Targeting of Engineered Heterologous Antigens Is a Determinant Factor for Bovine Herpesvirus 4-Based Vaccine Vector Development

In a previous study, an apathogenic strain of bovine herpesvirus 4 (BoHV-4) cloned as a bacterial artificial chromosome and expressing a chimeric peptide (gE2/gD) as a secreted form was described. Recombinant virus-inoculated animals produced antibodies against bovine viral diarrhea virus (BVDV) gE2...

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Bibliographische Detailangaben
Hauptverfasser: Donofrio, Gaetano, Franceschi, Valentina, Capocefalo, Antonio, Taddei, Simone, Sartori, Chiara, Bonomini, Sabrina, Cavirani, Sandro, Cabassi, Clotilde S., Flammini, Cesidio F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Veterinary Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772392/
https://ncbi.nlm.nih.gov/pubmed/19793901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00224-09
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