Dramatic Co-Activation of WWOX/WOX1 with CREB and NF-κB in Delayed Loss of Small Dorsal Root Ganglion Neurons upon Sciatic Nerve Transection in Rats

BACKGROUND: Tumor suppressor WOX1 (also named WWOX or FOR) is known to participate in neuronal apoptosis in vivo. Here, we investigated the functional role of WOX1 and transcription factors in the delayed loss of axotomized neurons in dorsal root ganglia (DRG) in rats. METHODOLOGY/PRINCIPAL FINDINGS...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Li, Meng-Yen, Lai, Feng-Jie, Hsu, Li-Jin, Lo, Chen-Peng, Cheng, Ching-Li, Lin, Sing-Ru, Lee, Ming-Hui, Chang, Jean-Yun, Subhan, Dudekula, Tsai, Ming-Shu, Sze, Chun-I, Pugazhenthi, Subbiah, Chang, Nan-Shan, Chen, Shur-Tzu
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2009
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771921/
https://ncbi.nlm.nih.gov/pubmed/19918364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007820
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