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The first 30 years of p53: growing ever more complex

Thirty years ago, p53 was discovered as a cellular partner of SV40 Large Tumor Antigen, the oncoprotein of this tumor virus. The first decade of p53 research saw the cloning of p53 DNA and the realization that p53 is not an oncogene but a tumor suppressor that is very frequently mutated in human can...

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Detalhes bibliográficos
Main Authors: Levine, Arnold J., Oren, Moshe
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771725/
https://ncbi.nlm.nih.gov/pubmed/19776744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2723
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