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Building a dictionary for genomes: Identification of presumptive regulatory sites by statistical analysis

The availability of complete genome sequences and mRNA expression data for all genes creates new opportunities and challenges for identifying DNA sequence motifs that control gene expression. An algorithm, “MobyDick,” is presented that decomposes a set of DNA sequences into the most probable diction...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Bussemaker, Harmen J., Li, Hao, Siggia, Eric D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27717/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10944202/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.180265397
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