Toxicity Profile and Pharmacokinetic Study of A Phase I Low-Dose Schedule-Dependent Radiosensitizing Paclitaxel Chemoradiation Regimen for Inoperable Non-Small Cell Lung Cancer (NSCLC)

PURPOSE: We report the toxicity profile and pharmacokinetic data of a schedule-dependent chemoradiation regimen using pulsed low-dose paclitaxel for radiosensitization in a phase I study for inoperable non-small cell lung cancer (NSCLC). METHODS AND MATERIALS: Paclitaxel at escalating doses of 15 mg...

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Main Authors: Chen, Yuhchyau, Pandya, Kishan J., Feins, Richard, Johnstone, David W., Watson, Thomas, Smudzin, Therese, Keng, Peter C.
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771614/
https://ncbi.nlm.nih.gov/pubmed/18164866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2007.10.011
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