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THE CONTRIBUTION OF CONFORMATIONAL ADJUSTMENTS AND LONG-RANGE ELECTROSTATIC FORCES TO THE CD2/CD58 INTERACTION
CD2 is a T cell surface molecule that enhances T and Natural Killer cell function by binding its ligands CD58 (humans) and CD48 (rodents) on antigen presenting or target cells. Here we show that the CD2/CD58 interaction is enthalpically-driven and accompanied by unfavourable entropic changes. Taken...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771598/ https://ncbi.nlm.nih.gov/pubmed/17344209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M700829200 |
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