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Differential effects of Latrunculin-A on myofibrils in cultures of skeletal muscle cells: Insights into mechanisms of myofibrillogenesis

To explore the changes in actin filaments during the process of myofibrillogenesis, primary cultures of avian skeletal muscle cells were exposed to Latrunculin-A (Lat-A), a drug that binds monomeric actin. Lat-A, at low concentrations (0.2 – 0.5µM) had no effect on actin fibers in the myotubes, but...

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Detalhes bibliográficos
Main Authors: Wang, Jushuo, Sanger, Jean M., Sanger, Joseph W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771450/
https://ncbi.nlm.nih.gov/pubmed/16080205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.20083
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