The structure of Plasmodium falciparum EBA175 ligand domain and the molecular basis of host specificity

One of the best-characterized Plasmodium falciparum merozoite ligands is EBA175, whose recognition of glycophorin A is dependent upon terminal sialic acids of this erythrocyte glycoprotein. The recently solved crystal structure of EBA175 reveals that a critical factor for erythrocyte recognition is...

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Bibliographic Details
Main Authors: Chattopadhyay, D., Rayner, J.C., McHenry, A.M., Adams, J. H.
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771403/
https://ncbi.nlm.nih.gov/pubmed/16497558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pt.2006.02.007
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