A Drug-Sensitized Zebrafish Screen Identifies Multiple Genes, Including GINS3, as Regulators of Myocardial Repolarization

BACKGROUND: Cardiac repolarization, the process by which cardiomyocytes return to their resting potential after each beat, is a highly regulated process that is critical for heart rhythm stability. Perturbations of cardiac repolarization increase the risk for life-threatening arrhythmias and sudden...

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Hlavní autoři: Milan, David J., Kim, Albert M., Winterfield, Jeffrey R., Jones, Ian L., Pfeufer, Arne, Sanna, Serena, Arking, Dan E., Amsterdam, Adam H., Sabeh, Khaled M., Mably, John D., Rosenbaum, David S., Peterson, Randall T., Chakravarti, Aravinda, Kääb, Stefan, Roden, Dan M., MacRae, Calum A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771327/
https://ncbi.nlm.nih.gov/pubmed/19652097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.821082
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